A fact-finding mission by the UN`s chemical weapons watchdog has concluded that the banned nerve agent Sarin was used in an attack in northern Syria in April that killed dozens of people.
A UN panel will now try to determine if the Syrian government was responsible.
The attack on Khan Sheikhoun in Idlib province was the most deadly in Syria in more than three years.
It prompted a retaliatory US missile strike against a Syrian air base the US said had launched the attack.
The fact-finding mission for the Organisation for the Prohibition of Chemical Weapons (OPCW), which is based in The Hague, concluded that, after interviewing witnesses and examining samples, "a large number of people, some of whom died, were exposed to Sarin or a Sarin-like substance".
"It is the conclusion of the FFM (fact-finding mission) that such a release can only be determined as the use of Sarin, as a chemical weapon," a summary said.
The new report has been circulated among OPCW members but has not been made public.
A joint UN and OPCW investigation will now investigate who was to blame for the attack.
US President Donald Trump ordered a cruise missile strike on Shayrat air base after US officials concluded that the facility was where a Syrian Air Force jet had been armed with a Sarin-filled bomb.
Syrian President Bashar al-Assad has previously said that the incident was fabricated.
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